{"id":51062,"date":"2025-04-25T21:43:05","date_gmt":"2025-04-26T01:43:05","guid":{"rendered":"https:\/\/www.hancockhealth.org\/mayo-health-library\/l-arginine\/"},"modified":"2026-02-04T11:56:25","modified_gmt":"2026-02-04T16:56:25","slug":"l-arginine","status":"publish","type":"mayo","link":"https:\/\/hancockhealth.apgar.digital\/ja\/mayo-health-library\/l-arginine\/","title":{"rendered":"L-arginine"},"content":{"rendered":"<div class=\"container mx-auto   wordpress-block wordpress- core-\">\n<p>L-arginine is an amino acid that helps the body build protein.<\/p>\n<p>Your body usually makes all the L-arginine it needs. L-arginine is also found in most protein-rich foods, including fish, red meat, poultry, soy, whole grains, beans and dairy products.<\/p>\n<p>As a supplement, L-arginine can be used orally and topically. It can also be administered intravenously (IV).<\/p>\n<p>Because L-arginine acts as a vasodilator, opening (dilating) blood vessels, many people take oral L-arginine to treat heart conditions and erectile dysfunction.<\/p>\n<p>Research on the use of L-arginine for specific conditions shows:<\/p>\n<ul>\n<li><strong>Angina.<\/strong> Studies suggest that L-arginine might decrease symptoms and improve quality of life in people with a mild to severe form of this type of chest pain.<\/li>\n<li><strong>High blood pressure (hypertension).<\/strong> Some research has shown that oral L-arginine can lower blood pressure in healthy people, people with mild blood pressure elevation and diabetes, and in people with a type of high blood pressure that affects the arteries in the lungs and the right side of the heart (pulmonary hypertension). Infusions of L-arginine also appear to lower blood pressure in people with hypertension.<\/li>\n<li><strong>High blood pressure during pregnancy.<\/strong> Some studies show that L-arginine infusions may lower blood pressure in pregnant women who develop high blood pressure.<\/li>\n<li><strong>Preeclampsia.<\/strong> L-arginine infusions may lower blood pressure in women with this pregnancy complication. Some research shows that taking oral L-arginine might help prevent preeclampsia in pregnant women.<\/li>\n<li><strong>Erectile dysfunction.<\/strong> Taking oral L-arginine might improve sexual function in men with erectile dysfunction due to a physical cause.<\/li>\n<li><strong>Peripheral arterial disease (PAD).<\/strong> When taken orally or by infusion for a short period of time, L-arginine may improve symptoms and blood flow in people with this circulatory condition.<\/li>\n<\/ul>\n<h4>Generally safe<\/h4>\n<p>L-arginine is considered to be generally safe. It might be effective at lowering blood pressure, reducing the symptoms of angina and <abbr title=\"peripheral arterial disease\">PAD<\/abbr>, and treating erectile dysfunction due to a physical cause.<\/p>\n<p>However, if you take a blood pressure drug, talk to your doctor before using L-arginine.<\/p>\n<p>Using L-arginine orally or topically is generally considered safe.<\/p>\n<p>Oral use of L-arginine might cause:<\/p>\n<ul>\n<li>Nausea, abdominal pain and diarrhea<\/li>\n<li>Bloating<\/li>\n<li>Gout<\/li>\n<li>Headache<\/li>\n<li>Allergic response<\/li>\n<li>Airway inflammation or worsening of asthma symptoms<\/li>\n<\/ul>\n<p>L-arginine isn&#8217;t recommended for people who have had a recent heart attack due to concerns that the supplement might increase the risk of death.<\/p>\n<p>L-arginine can worsen allergies or asthma. Use the supplement with caution if you have these conditions.<\/p>\n<p>Be careful about taking L-arginine if you&#8217;ve had cold sores or genital herpes. Too much L-arginine in your system can potentially trigger the virus that causes those conditions.<\/p>\n<p>Possible interactions include:<\/p>\n<ul>\n<li><strong>Anticoagulants and anti-platelet drugs, herbs and supplements.<\/strong> These types of drugs, herbs and supplements reduce blood clotting. Taking L-arginine with them might increase the risk of bleeding.<\/li>\n<li><strong>Blood pressure drugs, herbs and supplements.<\/strong> L-arginine might lower blood pressure in people who have high blood pressure. Combining use of L-arginine with a blood pressure drug, herb or supplement might increase the risk of blood pressure becoming too low.<\/li>\n<li><strong>Diabetes drugs, herbs and supplements.<\/strong> L-arginine might decrease blood sugar levels in people with diabetes. If you&#8217;re taking diabetes drugs, herbs or supplements, your dosage might need to be adjusted.<\/li>\n<li><strong>Isoproterenol (Isuprel).<\/strong> Use of this heart medication with L-arginine might cause your blood pressure to become too low.<\/li>\n<li><strong>Nitrates.<\/strong> Use of this chest pain medication with L-arginine might cause your blood pressure to become too low.<\/li>\n<li><strong>Water pills (potassium-sparing diuretics).<\/strong> Don&#8217;t take L-arginine with amiloride (Midamor), spironolactone (Aldactone, Carospir) or triamterene (Dyrenium). These medications can increase potassium levels, increasing the risk of developing a higher than normal level of potassium in your blood (hyperkalemia).<\/li>\n<li><strong>Sildenafil (Revatio, Viagra).<\/strong> Use of this erectile dysfunction medication with L-arginine might cause your blood pressure to become too low.<\/li>\n<\/ul>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Understand how L-arginine affects blood vessels and when to avoid using this supplement.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","tags":[1722],"class_list":["post-51062","mayo","type-mayo","status-publish","hentry","tag-l-arginine","content_type-articles"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L-arginine - Hancock Health<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L-arginine - 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